ANTI-INFECTIVE AGENTS:
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Drugs designed to act selectively on foreign organisms that have invaded and infected the body.
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Range from:
- Antibiotics
- Antifungal
- Antiprotozoal
- Antihelmintics
- Antiviral
- Antimycobacterial
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General Mechanism of Action:
- Some interfere with the biosynthesis of CELL WALL.
- Some inhibits CHON synthesis
- Some change the cell membrane permeability
- Some inhibit DNA synthesis
The following videos show the mechanism of actions of certain classes of anti-infective drugs as well as how microorganisms develop resistance against them.
*After viewing all videos, kindly post your learning and/or reactions by answering the following questions in the comment box. This will serve as a one of your requirements in Pharmacology.
1. What are the pharmacologic implications of the differences in human and microbial cell structures?
2. How does each of the agents fight back infection?
3. What are the possible challenges and limitations that an anti-infective drug can encounter now and in the future?
1. What are the pharmacologic implications of the differences in human and microbial cell structures?
2. How does each of the agents fight back infection?
3. What are the possible challenges and limitations that an anti-infective drug can encounter now and in the future?
ANTIBIOTICS & HOW THEY TREAT INFECTION
BETA-LACTAM MECHANISM OF ACTION
MACROLIDE MECHANISM OF ACTION
FLUOROQUINOLONES MECHANISM OF ACTION
